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Thioflavin T as a fluorescence light-up probe for G4 formation

Thioflavin T (ThT) becomes fluorescent in the presence of the G-quadruplex structure such as that formed by the human telomeric motif. In this report, we extend and generalize these observations and show that this dye may be used as a convenient and specific quadruplex probe. In the presence of most...

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Bibliographische Detailangaben
Hauptverfasser: Renaud de la Faverie, Amandine, Guédin, Aurore, Bedrat, Amina, Yatsunyk, Liliya A., Mergny, Jean-Louis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005661/
https://ncbi.nlm.nih.gov/pubmed/24510097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku111
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