HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters

Active positive transcription elongation factor b (P-TEFb) is essential for cellular and human immunodeficiency virus type 1 (HIV-1) transcription elongation. CTIP2 represses P-TEFb activity in a complex containing 7SK RNA and HEXIM1. Recently, the inactive 7SK/P-TEFb small nuclear RNP (snRNP) has b...

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Hlavní autoři: Eilebrecht, Sebastian, Le Douce, Valentin, Riclet, Raphael, Targat, Brice, Hallay, Houda, Van Driessche, Benoît, Schwartz, Christian, Robette, Gwenaëlle, Van Lint, Carine, Rohr, Olivier, Benecke, Arndt G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005653/
https://ncbi.nlm.nih.gov/pubmed/24623795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku168
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