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Regulation of promoter-proximal transcription elongation: enhanced DNA scrunching drives λQ antiterminator-dependent escape from a σ70-dependent pause

During initial transcription, RNA polymerase remains bound at the promoter and synthesizes RNA without movement along the DNA template, drawing downstream DNA into itself in a process called scrunching and thereby storing energy to sever the bonds that hold the enzyme at the promoter. We show that D...

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Detalhes bibliográficos
Main Authors: Strobel, Eric J., Roberts, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005639/
https://ncbi.nlm.nih.gov/pubmed/24550164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku147
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