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Genetic and Biochemical Characterization of a Chromosome-Encoded Carbapenem-Hydrolyzing Ambler Class D β-Lactamase from Shewanella algae

A chromosome-encoded β-lactamase gene from Shewanella algae clinical isolate KB-1 was cloned and expressed in Escherichia coli. It encoded the Ambler class D enzyme OXA-55, sharing less than 55% identity with any other oxacillinases. Although conferring a narrow-spectrum β-lactam resistance phenotyp...

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Main Authors: Héritier, Claire, Poirel, Laurent, Nordmann, Patrice
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC400541/
https://ncbi.nlm.nih.gov/pubmed/15105119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1670-1675.2004
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