Genetic and Biochemical Characterization of a Chromosome-Encoded Carbapenem-Hydrolyzing Ambler Class D β-Lactamase from Shewanella algae

A chromosome-encoded β-lactamase gene from Shewanella algae clinical isolate KB-1 was cloned and expressed in Escherichia coli. It encoded the Ambler class D enzyme OXA-55, sharing less than 55% identity with any other oxacillinases. Although conferring a narrow-spectrum β-lactam resistance phenotyp...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Héritier, Claire, Poirel, Laurent, Nordmann, Patrice
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Mechanisms of Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1670-1675.2004
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