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Iron Blocks the Accumulation and Activity of Tetracyclines in Bacteria
The apparent sensitivities of several bacterial pathogens to tetracyclines varied by up to 128-fold with the medium content of Fe, but not of other metals. The effect of Fe was independent of superoxide dismutase activity and of intracellular Fe, but accumulation of tetracyclines was blocked in high...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC400538/ https://ncbi.nlm.nih.gov/pubmed/15105154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1892-1894.2004 |
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