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Iron Blocks the Accumulation and Activity of Tetracyclines in Bacteria

The apparent sensitivities of several bacterial pathogens to tetracyclines varied by up to 128-fold with the medium content of Fe, but not of other metals. The effect of Fe was independent of superoxide dismutase activity and of intracellular Fe, but accumulation of tetracyclines was blocked in high...

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Detalhes bibliográficos
Main Authors: Avery, Angela M., Goddard, Helen J., Sumner, Edward R., Avery, Simon V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400538/
https://ncbi.nlm.nih.gov/pubmed/15105154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1892-1894.2004
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