Direct Action of Endothelin-1 on Podocytes Promotes Diabetic Glomerulosclerosis

The endothelin system has emerged as a novel target for the treatment of diabetic nephropathy. Endothelin-1 promotes mesangial cell proliferation and sclerosis. However, no direct pathogenic effect of endothelin-1 on podocytes has been shown in vivo and endothelin-1 signaling in podocytes has not be...

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Dettagli Bibliografici
Autori principali: Lenoir, Olivia, Milon, Marine, Virsolvy, Anne, Hénique, Carole, Schmitt, Alain, Massé, Jean-Marc, Kotelevtsev, Yuri, Yanagisawa, Masashi, Webb, David J., Richard, Sylvain, Tharaux, Pierre-Louis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2014
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005294/
https://ncbi.nlm.nih.gov/pubmed/24722437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013020195
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