Brain White Matter Development Is Associated with a Human-Specific Haplotype Increasing the Synthesis of Long Chain Fatty Acids

The genetic and molecular pathways driving human brain white matter (WM) development are only beginning to be discovered. Long chain polyunsaturated fatty acids (LC-PUFAs) have been implicated in myelination in animal models and humans. The biosynthesis of LC-PUFAs is regulated by the fatty acid des...

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Detalhes bibliográficos
Main Authors: Peters, Bart D., Voineskos, Aristotle N., Szeszko, Philip R., Lett, Tristram A., DeRosse, Pamela, Guha, Saurav, Karlsgodt, Katherine H., Ikuta, Toshikazu, Felsky, Daniel, John, Majnu, Rotenberg, David J., Kennedy, James L., Lencz, Todd, Malhotra, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004819/
https://ncbi.nlm.nih.gov/pubmed/24790207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2818-13.2014
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