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Dissection of the Critical Binding Determinants of Cellular Retinoic Acid Binding Protein II by Mutagenesis and Fluorescence Binding Assay

The binding of retinoic acid to mutants of Cellular Retinoic Acid Binding Protein II (CRABPII) was evaluated to better understand the importance of the direct protein/ligand interactions. The important role of Arg111 for the correct structure and function of the protein was verified and other residu...

詳細記述

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書誌詳細
主要な著者: Vasileiou, Chrysoula, Lee, Kin Sing Stephen, Crist, Rachael M., Vaezeslami, Soheila, Goins, Sarah M., Geiger, James H., Borhan, Babak
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004609/
https://ncbi.nlm.nih.gov/pubmed/19156818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22334
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