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Dissection of the Critical Binding Determinants of Cellular Retinoic Acid Binding Protein II by Mutagenesis and Fluorescence Binding Assay

The binding of retinoic acid to mutants of Cellular Retinoic Acid Binding Protein II (CRABPII) was evaluated to better understand the importance of the direct protein/ligand interactions. The important role of Arg111 for the correct structure and function of the protein was verified and other residu...

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Bibliografiske detaljer
Main Authors: Vasileiou, Chrysoula, Lee, Kin Sing Stephen, Crist, Rachael M., Vaezeslami, Soheila, Goins, Sarah M., Geiger, James H., Borhan, Babak
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004609/
https://ncbi.nlm.nih.gov/pubmed/19156818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22334
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