Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity

The nuclear pore complex (NPC) has dual roles in nucleocytoplasmic transport and chromatin organization. In many eukaryotes the coiled-coil Mlp/Tpr proteins of the NPC nuclear basket have specific functions in interactions with chromatin and defining specialized regions of active transcription, wher...

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Detalhes bibliográficos
Main Authors: Holden, Jennifer M., Koreny, Ludek, Obado, Samson, Ratushny, Alexander V., Chen, Wei-Ming, Chiang, Jung-Hsien, Kelly, Steven, Chait, Brian T., Aitchison, John D., Rout, Michael P., Field, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004592/
https://ncbi.nlm.nih.gov/pubmed/24600046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-12-0750
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