Essential Role of TEA Domain Transcription Factors in the Negative Regulation of the MYH 7 Gene by Thyroid Hormone and Its Receptors

MYH7 (also referred to as cardiac myosin heavy chain β) gene expression is known to be repressed by thyroid hormone (T3). However, the molecular mechanism by which T3 inhibits the transcription of its target genes (negative regulation) remains to be clarified, whereas those of transcriptional activa...

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Bibliographic Details
Main Authors: Iwaki, Hiroyuki, Sasaki, Shigekazu, Matsushita, Akio, Ohba, Kenji, Matsunaga, Hideyuki, Misawa, Hiroko, Oki, Yutaka, Ishizuka, Keiko, Nakamura, Hirotoshi, Suda, Takafumi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004540/
https://ncbi.nlm.nih.gov/pubmed/24781449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088610
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