Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase SH-PTP1.
SH-PTP1 (also known as PTP1C, HCP, and SHP) is a non-transmembrane protein tyrosine phosphatase (PTPase) containing two tandem Src homology 2 (SH2) domains. We show here that the two SH2 (N-SH2 and C-SH2) domains in SH-PTP1 have different functions in regulation of the PTPase domain and thereby sign...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8577729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.3.1141 |
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