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Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during different phases of T cell responses: implications for arthritis and autoimmune diseases

Chronic T cell responses, as they occur in rheumatoid arthritis, are complex and are likely to involve many mechanisms. There is a growing body of evidence that, in concert with the T cell antigen receptor signal, CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4; CD152) are the primary regulators o...

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Autors principals: Brunner-Weinzierl, Monika C, Hoff, Holger, Burmester, Gerd-R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC400439/
https://ncbi.nlm.nih.gov/pubmed/15059264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1158
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