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Toll-like receptor 9 activation: a novel mechanism linking placenta-derived mitochondrial DNA and vascular dysfunction in preeclampsia

Emerging evidence suggests that in addition of being the “power houses” of our cells, mitochondria facilitate effector responses of the immune system. Cell death and injury result in the release of mitochondrial DNA (mtDNA) that acts via Toll-like receptor 9 (TLR9), a pattern recognition receptor of...

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Hlavní autoři: Goulopoulou, Styliani, Matsumoto, Takayuki, Bomfim, Gisele F., Webb, R. Clinton
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004352/
https://ncbi.nlm.nih.gov/pubmed/22671429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20120130
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