Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4

It was recently shown that mouse fibroblasts could be reprogrammed into cells of a cardiac fate by forced expression of multiple transcription factors and microRNAs. To ultimately apply such reprogramming strategy for cell-based therapy or in vivo cardiac regeneration, reducing or eliminating the ge...

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Main Authors: Wang, Haixia, Cao, Nan, Spencer, C. Ian, Nie, Baoming, Ma, Tianhua, Xu, Tao, Zhang, Yu, Wang, Xiaojing, Srivastava, Deepak, Ding, Sheng
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004339/
https://ncbi.nlm.nih.gov/pubmed/24561253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.01.038
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