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A condition-specific codon optimization approach for improved heterologous gene expression in Saccharomyces cerevisiae

BACKGROUND: Heterologous gene expression is an important tool for synthetic biology that enables metabolic engineering and the production of non-natural biologics in a variety of host organisms. The translational efficiency of heterologous genes can often be improved by optimizing synonymous codon u...

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Bibliografiske detaljer
Main Authors: Lanza, Amanda M, Curran, Kathleen A, Rey, Lindsey G, Alper, Hal S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004289/
https://ncbi.nlm.nih.gov/pubmed/24636000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-33
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