Protein-Triggered Supramolecular Disassembly: Insights Based on Variations in Ligand Location in Amphiphilic Dendrons

[Image: see text] We use monodisperse dendrons that allow control over functional group presentation to investigate the influence of the location of a ligand on protein-induced disassembly and release of encapsulated small molecules. Based on both experiments and molecular dynamics simulations, we d...

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Main Authors: Amado Torres, Diego, Garzoni, Matteo, Subrahmanyam, Ayyagari V., Pavan, Giovanni M., Thayumanavan, S.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004214/
https://ncbi.nlm.nih.gov/pubmed/24641469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500634u
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