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Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells

In the ovary, connexin-coupled gap junctions in granulosa cells play crucial roles in follicular and oocyte development as well as in corpus luteum formation. Our previous work has shown that theca cell-derived bone morphogenetic protein (BMP)4 and BMP7 decrease gap junction intercellular communicat...

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書誌詳細
主要な著者: Chang, Hsun-Ming, Cheng, Jung-Chien, Taylor, Elizabeth, Leung, Peter C.K.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004082/
https://ncbi.nlm.nih.gov/pubmed/24413384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gau001
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