Acute Infection with Epstein-Barr Virus Targets and Overwhelms the Peripheral Memory B-Cell Compartment with Resting, Latently Infected Cells

In this paper we demonstrate that during acute infection with Epstein-Barr virus (EBV), the peripheral blood fills up with latently infected, resting memory B cells to the point where up to 50% of all the memory cells may carry EBV. Despite this massive invasion of the memory compartment, the virus...

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Hlavní autoři: Hochberg, Donna, Souza, Tatyana, Catalina, Michelle, Sullivan, John L., Luzuriaga, Katherine, Thorley-Lawson, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC400374/
https://ncbi.nlm.nih.gov/pubmed/15113901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5194-5204.2004
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