Identification of the Nuclear Export Signal and STAT-Binding Domains of the Nipah Virus V Protein Reveals Mechanisms Underlying Interferon Evasion

The V proteins of Nipah virus and Hendra virus have been demonstrated to bind to cellular STAT1 and STAT2 proteins to form high-molecular-weight complexes that inhibit interferon (IFN)-induced antiviral transcription by preventing STAT nuclear accumulation. Analysis of the Nipah virus V protein has...

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Bibliographic Details
Main Authors: Rodriguez, Jason J., Cruz, Cristian D., Horvath, Curt M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400366/
https://ncbi.nlm.nih.gov/pubmed/15113915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5358-5367.2004
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