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Wide Variations in Herpes Simplex Virus Type 1 Inoculum Dose and Latency-Associated Transcript Expression Phenotype Do Not Alter the Establishment of Latency in the Rabbit Eye Model

The latency-associated transcript (LAT) is required for efficient reactivation of herpes simplex virus type 1 from latent infection in the rabbit eye model, but LAT's mechanism of action is unknown. In addition to reactivation, the LAT region seems to correspond to multiple functions, with some...

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Detalhes bibliográficos
Main Authors: O'Neil, J. E., Loutsch, J. M., Aguilar, J. S., Hill, J. M., Wagner, E. K., Bloom, D. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400357/
https://ncbi.nlm.nih.gov/pubmed/15113885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5038-5044.2004
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