King Cobra (Ophiophagus hannah) Venom L-Amino Acid Oxidase Induces Apoptosis in PC-3 Cells and Suppresses PC-3 Solid Tumor Growth in a Tumor Xenograft Mouse Model

King cobra (Ophiophagus hannah) venom L-amino acid oxidase (OH-LAAO), a heat stable enzyme, has been shown to exhibit very potent anti-proliferative activity against human breast and lung tumorigenic cells but not in their non-tumorigenic counterparts. We further examine its in vitro and in vivo ant...

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Autori principali: Lee, Mui Li, Fung, Shin Yee, Chung, Ivy, Pailoor, Jayalakshmi, Cheah, Swee Hung, Tan, Nget Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003544/
https://ncbi.nlm.nih.gov/pubmed/24782648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.8096
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