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Unspliced Rous Sarcoma Virus Genomic RNAs Are Translated and Subjected to Nonsense-Mediated mRNA Decay before Packaging

Retroviruses package full-length, unspliced RNAs into progeny virions as dimerized RNA genomes. They also use unspliced RNAs as mRNAs to produce the gag and pol gene products. We asked whether a single Rous sarcoma virus (RSV) RNA can be translated and subsequently packaged or whether genomic packag...

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Udgivet i:J Virol
Principais autores: LeBlanc, Jason J., Beemon, Karen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400353/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15113896/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.10.5139-5146.2004
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