CD8(+)-Cell-Mediated Suppression of Virulent Simian Immunodeficiency Virus during Tenofovir Treatment

The ability of tenofovir to suppress viremia in simian immunodeficiency virus (SIV)-infected macaques for years despite the presence of virulent viral mutants with reduced in vitro susceptibility is unprecedented in this animal model. In vivo cell depletion experiments demonstrate that tenofovir...

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Detalhes bibliográficos
Main Authors: Van Rompay, Koen K. A., Singh, Raman P., Pahar, Bapi, Sodora, Donald L., Wingfield, Casey, Lawson, Jonathan R., Marthas, Marta L., Bischofberger, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400346/
https://ncbi.nlm.nih.gov/pubmed/15113912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5324-5337.2004
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