Selective expansion of human natural killer cells leads to enhanced alloreactivity

In allogeneic stem cell transplantation (SCT), natural killer (NK) cells lacking their cognate inhibitory ligand can induce graft-versus-leukemia responses, without the induction of severe graft-versus-host disease (GVHD). This feature can be exploited for cellular immunotherapy. In this study, we e...

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Detalhes bibliográficos
Main Authors: Eissens, Diana N, Michelo, Clive M, Preijers, Frank WMB, van Cranenbroek, Bram, van Houwelingen, Kjeld, van der Meer, Arnold, Joosten, Irma
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003378/
https://ncbi.nlm.nih.gov/pubmed/24240123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.56
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