Retinol induces morphological alterations and proliferative focus formation through free radical-mediated activation of multiple signaling pathways

AIM: Toxicity of retinol (vitamin A) has been previously associated with apoptosis and/or cell malignant transformation. Thus, we investigated the pathways involved in the induction of proliferation, deformation and proliferative focus formation by retinol in cultured Sertoli cells of rats. METHODS:...

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Detalhes bibliográficos
Main Authors: Gelain, Daniel Pens, Pasquali, Matheus Augusto de Bittencourt, Caregnato, Fernanda Freitas, Castro, Mauro Antonio Alves, Moreira, José Claudio Fonseca
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003367/
https://ncbi.nlm.nih.gov/pubmed/22426700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.202
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