Polygalasaponin F induces long-term potentiation in adult rat hippocampus via NMDA receptor activation

AIM: To investigate the effect and underlying mechanisms of polygalasaponin F (PGSF), a triterpenoid saponin isolated from Polygala japonica, on long-term potentiation (LTP) in hippocampus dentate gyrus (DG) of anesthetized rats. METHODS: Population spike (PS) of hippocampal DG was recorded in anest...

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Main Authors: Sun, Feng, Sun, Jian-dong, Han, Ning, Li, Chuang-jun, Yuan, Yu-he, Zhang, Dong-ming, Chen, Nai-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003366/
https://ncbi.nlm.nih.gov/pubmed/22286914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.199
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