Synergism of irbesartan and amlodipine on hemodynamic amelioration and organ protection in spontaneously hypertensive rats

AIM: To investigate the synergism of low-doses of amlodipine and irbesartan on reduction of blood pressure variability (BPV), amelioration of baroreflex sensitivity (BRS) and organ protection in spontaneously hypertensive rats (SHR). METHODS: The rats were administered amlodipine (1 mg·kg(−1)·d(−1))...

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Главные авторы: Shang, Wen, Han, Ping, Yang, Cheng-bing, Gu, Xiao-wen, Zhang, Wei, Xu, Li-ping, Fu, Shou-ting, Su, Ding-feng, Xie, He-hui
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003304/
https://ncbi.nlm.nih.gov/pubmed/21804575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.88
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