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T33, a novel peroxisome proliferator-activated receptor γ/α agonist, exerts neuroprotective action via its anti-inflammatory activities

AIM: To examine the neuroprotective effects of T33, a peroxisome proliferator-activated receptor gamma/alpha (PPARγ/α) agonist, in acute ischemic models in vitro and in vivo. METHODS: Primary astrocytes subjected to oxygen-glucose deprivation/reperfusion (O/R) and BV-2 cells subjected to hypoxia wer...

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Detalhes bibliográficos
Main Authors: Wang, Ying, Yang, Yu-she, Tang, Xi-can, Zhang, Hai-yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003300/
https://ncbi.nlm.nih.gov/pubmed/21804572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.69
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