HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles

Fibro-adipogenic progenitors (FAPs) are important components of the skeletal muscle regenerative environment. Whether FAPs support muscle regeneration or promote fibro-adipogenic degeneration is emerging as a key determinant in the pathogenesis of muscular diseases, including Duchenne muscular dystr...

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Autori principali: Saccone, Valentina, Consalvi, Silvia, Giordani, Lorenzo, Mozzetta, Chiara, Barozzi, Iros, Sandoná, Martina, Ryan, Tammy, Rojas-Muñoz, Agustin, Madaro, Luca, Fasanaro, Pasquale, Borsellino, Giovanna, De Bardi, Marco, Frigè, Gianmaria, Termanini, Alberto, Sun, Xin, Rossant, Janet, Bruneau, Benoit G., Mercola, Mark, Minucci, Saverio, Puri, Pier Lorenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003277/
https://ncbi.nlm.nih.gov/pubmed/24682306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.234468.113
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