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Immunosuppressant discovery from Tripterygium wilfordii Hook f: the novel triptolide analog (5R)-5-hydroxytriptolide (LLDT-8)

The Chinese traditional herb Tripterygium wilfordii Hook f (TwHF) has been widely used in the treatment of autoimmune and inflammatory diseases. Over the past few decades, great efforts have been made to explore modern preparations of TwHF with higher efficacy, solubility, and lower toxicity. In thi...

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Detalhes bibliográficos
Main Authors: Tang, Wei, Zuo, Jian-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003106/
https://ncbi.nlm.nih.gov/pubmed/22922344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.108
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