B-cell-targeted therapies in systemic lupus erythematosus

Autoreactive B cells are one of the key immune cells that have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). In addition to the production of harmful auto-antibodies (auto-Abs), B cells prime autoreactive T cells as antigen-presenting cells and secrete a wide range of pr...

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Bibliographic Details
Main Authors: Chan, Vera Sau-Fong, Tsang, Helen Hoi-Lun, Tam, Rachel Chun-Yee, Lu, Liwei, Lau, Chak-Sing
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003049/
https://ncbi.nlm.nih.gov/pubmed/23455017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.64
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