TLR4 inactivation protects from graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Graft-versus-host disease (GVHD) is the most common complication after hematopoietic stem cell transplantation. To clarify the role of Toll-like receptor 4 (TLR4), which is a major receptor for bacterial lipopolysaccharides (LPS), in the development of acute GVHD, we used a TLR4-knockout (TLR4(−/−))...

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Autores principales: Zhao, Yi, Liu, Qiuyan, Yang, Li, He, Donghua, Wang, Lijuan, Tian, Jun, Li, Yi, Zi, Fuming, Bao, Hanying, Yang, Yang, Zheng, Yuanyuan, Shi, Jimin, Xue, Xingkui, Cai, Zhen
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003043/
https://ncbi.nlm.nih.gov/pubmed/23262974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.58
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