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Magnesium lithospermate B dilates mesenteric arteries by activating BK(Ca) currents and contracts arteries by inhibiting K(V) currents

AIM: To examine the involvement of K(+) channels and endothelium in the vascular effects of magnesium lithospermate B (MLB), a hydrophilic active component of Salviae miltiorrhiza Radix. METHODS: Isolated rat mesenteric artery rings were employed to investigate the effects of MLB on KCl- or norepine...

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Detalhes bibliográficos
Main Authors: Zhang, Hai-fei, Chen, Xue-qing, Hu, Guo-yuan, Wang, Yi-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002966/
https://ncbi.nlm.nih.gov/pubmed/20453873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.40
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