Apolipoprotein A-I inhibits LPS-induced atherosclerosis in ApoE(−/−) mice possibly via activated STAT3-mediated upregulation of tristetraprolin

AIM: To investigate the effects of the major component of high-density lipoprotein apolipoprotein A-I (apoA-I) on the development of atherosclerosis in LPS-challenged ApoE(−/−) mice and the underlying mechanisms. METHODS: Male ApoE-KO mice were daily injected with LPS (25 μg, sc) or PBS for 4 weeks....

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Main Authors: Yin, Kai, Tang, Shi-lin, Yu, Xiao-hua, Tu, Guang-hui, He, Rong-fang, Li, Jin-feng, Xie, Di, Gui, Qing-jun, Fu, Yu-chang, Jiang, Zhi-sheng, Tu, Jian, Tang, Chao-ke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002890/
https://ncbi.nlm.nih.gov/pubmed/23564081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.10
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