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Downregulation of Dickkopf-1 is responsible for high proliferation of breast cancer cells via losing control of Wnt/β-catenin signaling

AIM: To investigate the role of DKK-1/Wnt/β-catenin signaling in high proliferation of LM-MCF-7 breast cancer cells, a sub-clone of MCF-7 cell line. METHODS: Two cell lines (MCF-7 and LM-MCF-7) with different proliferation abilities were used. LM-MCF-7 cells were transiently transfected with the pcD...

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Detalhes bibliográficos
Main Authors: Zhou, Xiao-lei, Qin, Xiao-ran, Zhang, Xiao-dong, Ye, Li-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002845/
https://ncbi.nlm.nih.gov/pubmed/20139903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.200
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