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Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells

AIM: To determine whether the flavonoid baicalin attenuates oxygen-glucose deprivation (OGD)-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase (5-LOX) activation in PC12 cells. METHODS: The effects of baicalin and the 5-LOX inhibitor zileuton on the changes induced by OGD/recover...

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Detalhes bibliográficos
Main Authors: Li, Cheng-tan, Zhang, Wei-ping, Fang, San-hua, Lu, Yun-bi, Zhang, Li-hui, Qi, Ling-ling, Huang, Xue-qin, Huang, Xiao-jia, Wei, Er-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002841/
https://ncbi.nlm.nih.gov/pubmed/20139896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.196
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