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The immunosuppressive effect of gossypol in mice is mediated by inhibition of lymphocyte proliferation and by induction of cell apoptosis

AIM: To investigate the immunosuppressive effect of gossypol in mice both in vitro and in vivo. METHODS: The in vitro effect of gossypol on the proliferation of lymphocytes isolated from lymph nodes of BALB/c mice was determined by CFSE staining and by an MTS assay. Lymphocyte activation and lymphob...

詳細記述

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書誌詳細
主要な著者: Xu, Wen-bin, Xu, Li-hui, Lu, Hong-song, Ou-Yang, Dong-yun, Shi, Huan-jing, Di, Jing-fang, He, Xian-hui
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002822/
https://ncbi.nlm.nih.gov/pubmed/19363517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.35
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