Genipin inhibits endothelial exocytosis via nitric oxide in cultured human umbilical vein endothelial cells

AIM: Exocytosis of endothelial Weibel-Palade bodies, which contain von Willebrand factor (VWF), P-selectin and other modulators, plays an important role in both inflammation and thrombosis. The present study investigates whether genipin, an aglycon of geniposide, inhibits endothelial exocytosis. MET...

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Hlavní autoři: Wang, Guang-fa, Wu, Shao-yu, Rao, Jin-jun, Lü, Lin, Xu, Wei, Pang, Jian-xin, Liu, Zhong-qiu, Wu, Shu-guang, Zhang, Jia-jie
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002818/
https://ncbi.nlm.nih.gov/pubmed/19349964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.31
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