The PI3K/Akt pathway mediates the protection of SO(2) preconditioning against myocardial ischemia/reperfusion injury in rats

AIM: To explore the mechanisms underlying the protection by SO(2) preconditioning against rat myocardial ischemia/reperfusion (I/R) injury. METHODS: Male Wistar rats underwent 30-min left coronary artery ligation followed by 120-min reperfusion. An SO(2) donor (1 μmol/kg) was intravenously injected...

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Main Authors: Zhao, Man-man, Yang, Jin-yan, Wang, Xin-bao, Tang, Chao-shu, Du, Jun-bao, Jin, Hong-fang
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002792/
https://ncbi.nlm.nih.gov/pubmed/23524571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.204
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