Inhibition of Hec1 expression enhances the sensitivity of human ovarian cancer cells to paclitaxel

AIM: Hec1, a member of the Ndc80 kinetochore complex, is highly expressed in cancers. The aim of this study was to explore the role and mechanism of action of Hec1 with respect to the cytotoxicity of paclitaxel in ovarian cancer. METHODS: Thirty ovarian cancer samples and 6 normal ovarian samples we...

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Autori principali: Mo, Qing-qing, Chen, Ping-bo, Jin, Xin, Chen, Qian, Tang, Lan, Wang, Bei-bei, Li, Ke-zhen, Wu, Peng, Fang, Yong, Wang, Shi-xuan, Zhou, Jian-feng, Ma, Ding, Chen, Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002790/
https://ncbi.nlm.nih.gov/pubmed/23474708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.197
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