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Bleomycin induces upregulation of lysyl oxidase in cultured human fetal lung fibroblasts

AIM: To investigate the mechanism of bleomycin (BLM)-induced pulmonary fibrosis. METHODS: Cultured human fetal lung fibroblast (HLF) cells were exposed to bleomycin (BLM) at 0–30 μg/mL for 24 h. Western blot analysis was used to detect lysyl oxidase (LO) protein expression. Real-time RT-PCR was used...

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書誌詳細
主要な著者: Chen, Li-jun, Li, Wan-de, Li, Shi-feng, Su, Xing-wen, Lin, Guang-yun, Huang, Yi-jun, Yan, Guang-mei
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002757/
https://ncbi.nlm.nih.gov/pubmed/20418892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.44
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