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GLP-1 receptor plays a critical role in geniposide-induced expression of heme oxygenase-1 in PC12 cells

AIM: To explore the role of activation of glucagon-like peptide 1 receptor (GLP-1R) and its relative cell signaling pathway in the cytoprotection of geniposide. METHODS: Cell viability was determined by MTT assay. Knockdown of the Glp-1r gene was carried out with shRNA. The levels of HO-1 protein an...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yin, Fei, Liu, Jian-hui, Zheng, Xu-xu, Guo, Li-xia
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002743/
https://ncbi.nlm.nih.gov/pubmed/20364157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.28
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