Hypomethylation of proximal CpG motif of interleukin-10 promoter regulates its expression in human rheumatoid arthritis

AIM: The promoter of human interleukin-10 (IL10), a cytokine crucial for suppressing inflammation and regulating immune responses, contains an interspecies-conserved sequence with CpG motifs. The aim of this study was to investigate whether methylation of CpG motifs could regulate the expression of...

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Detalhes bibliográficos
Main Authors: Fu, Li-hong, Ma, Chun-ling, Cong, Bin, Li, Shu-jin, Chen, Hai-ying, Zhang, Jing-ge
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002740/
https://ncbi.nlm.nih.gov/pubmed/21986577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.98
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