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RGD-FasL Induces Apoptosis in Hepatocellular Carcinoma

Despite impressive results obtained in animal models, the clinical use of Fas ligand (FasL) as an anticancer drug is limited by severe toxicity. Systemic toxicity of death ligands may be prevented by using genes encoding membrane-bound death ligands and by targeted transgene expression through eithe...

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Detalhes bibliográficos
Main Authors: Liu, Zhongchen, Wang, Juan, Yin, Ping, Qiu, Jinhua, Liu, Ruizhen, Li, Wenzhu, Fan, Xin, Cheng, Xiaofeng, Chen, Caixia, Zhang, Jiakai, Zhuang, Guohong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002720/
https://ncbi.nlm.nih.gov/pubmed/19728930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2009.38
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