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Krüppel-like factor (KLF) 5 mediates cyclin D1 expression and cell proliferation via interaction with c-Jun in Ang II-induced VSMCs
AIM: To elucidate how krüppel-like factor (KLF5) activates cyclin D1 expression in Ang II-induced vascular smooth muscle cells (VSMC) proliferation. METHODS: An adenoviral vector containing the full-length cDNA of KLF5 and a recombinant plasmid expressing c-Jun were constructed. MTT assay and flow c...
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Autori principali: | , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Nature Publishing Group
2010
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002698/ https://ncbi.nlm.nih.gov/pubmed/20037604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.185 |
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