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Krüppel-like factor (KLF) 5 mediates cyclin D1 expression and cell proliferation via interaction with c-Jun in Ang II-induced VSMCs

AIM: To elucidate how krüppel-like factor (KLF5) activates cyclin D1 expression in Ang II-induced vascular smooth muscle cells (VSMC) proliferation. METHODS: An adenoviral vector containing the full-length cDNA of KLF5 and a recombinant plasmid expressing c-Jun were constructed. MTT assay and flow c...

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Detalhes bibliográficos
Main Authors: Liu, Yu, Wen, Jin-kun, Dong, Li-hua, Zheng, Bin, Han, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002698/
https://ncbi.nlm.nih.gov/pubmed/20037604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.185
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