Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex

AIM: To prepare a bergenin-phospholipid complex (BPC) to increase oral bioavailability of the drug. METHODS: In order to obtain the acceptable BPC, a spherical symmetric design-response surface methodology was used for process optimization. The influence of reaction medium, temperature, drug concent...

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Main Authors: Qin, Xuan, Yang, Yang, Fan, Ting-ting, Gong, Tao, Zhang, Xiao-ning, Huang, Yuan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002688/
https://ncbi.nlm.nih.gov/pubmed/19966834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.171
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