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Analysis of the Conservation of T Cell Receptor Alpha and Beta Chain Variable Regions Gene in pp65 Peptide-Specific HLA-A(*)0201-Restricted CD8(+) T Cells

Many viral epitope specific T cell receptors (TCRs) in MHC-matched individuals have been demonstrated to involve conserved amino acid motifs in β chain complementarity-determining region 3 (CDR3). However, it is not sure whether the conserved motifs can also be found in TCR α chain. In previous stud...

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Detalhes bibliográficos
Main Authors: Luo, Wei, Ma, Li, Wen, Qian, Zhou, Mingqian, Wang, Xiaoning
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002646/
https://ncbi.nlm.nih.gov/pubmed/19403059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2009.14
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