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A new bisphosphonate derivative, CP, induces gastric cancer cell apoptosis via activation of the ERK1/2 signaling pathway

AIM: To investigate the effects of a new derivative of bisphosphonates, [2-(6-aminopurine-9-yl)-1-hydroxy-phosphine acyl ethyl] phosphonic acid (CP), on human gastric cancer. METHODS: Human gastric cancer cell lines (SGC-7901, BGC-823, MKN-45, and MKN-28) and human colon carcinoma cell lines (LoVo a...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Hai-jun, Liu, Yu, Fan, Li-qiao, Han, Cai-li, Jiang, Ye, Cheng, Shu-jie, Li, Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002562/
https://ncbi.nlm.nih.gov/pubmed/24241351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.103
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