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Improving the statistical detection of regulated genes from microarray data using intensity-based variance estimation

BACKGROUND: Gene microarray technology provides the ability to study the regulation of thousands of genes simultaneously, but its potential is limited without an estimate of the statistical significance of the observed changes in gene expression. Due to the large number of genes being tested and the...

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Autori principali: Comander, Jason, Natarajan, Sripriya, Gimbrone, Michael A, García-Cardeña, Guillermo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC400250/
https://ncbi.nlm.nih.gov/pubmed/15113402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-5-17
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