Oligomannurarate sulfate blocks tumor growth by inhibiting NF-κB activation

AIM: JG3, a novel marine-derived oligosaccharide, significantly inhibits angiogenesis and tumor metastasis by blocking heparanase activity. It also arrests tumor growth, an effect that is not fully explained by its anti-heparanase activity. Here we sought to identify the mechanisms underlying JG3-me...

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Detalhes bibliográficos
Main Authors: Zhang, Jing, Chen, Yi, Xin, Xian-liang, Li, Qiu-ning, Li, Ming, Lin, Li-ping, Geng, Mei-yu, Ding, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002413/
https://ncbi.nlm.nih.gov/pubmed/20154712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.13
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